Vivacit-E® Vitamin E Highly Crosslinked Polyethylene


Zimmer Biomet developed Vivacit-E Vitamin E Highly Crosslinked Polyethylene with antioxidant protection to meet the long-term performance needs of high demand patients. Building on the legacy of Longevity® Highly Crosslinked Polyethylene with more than 13 years of clinical success1, our proprietary process results in:

Exceptional Oxidative Stability2

It’s widely accepted that oxidation is a primary aging mechanism of polyethylene, which can lead to osteolysis and implant failure.12 The oxidative stability of Vivacit-E HXPE is the result of a proprietary process that grafts (locks) vitamin E directly to the polyethylene chain.6-9  The vitamin E continuously stabilizes the material to prevent oxidative degradation of the polyethylene. When subjected to accelerated aging for 33 weeks (16 times the industry standard), Vivacit-E HXPE showed no signs of oxidation or significant decline in mechanical properties.2

Ultra-low Wear3

The ultra-low wear rates of Longevity liners have been well established over 13 years of clinical history.1  In tests on 2 week-aged 40 mm articulation size Vivacit-E liners and Longevity liners, Vivacit-E liners showed ultra-low wear rates comparable to Longevity liners.3

To prove Vivacit-E HXPE’s long-term ultra-low wear properties a wear test was run out to 100 million cycles. The test proved Vivacit-E HXPE has ultra-low wear properties even after long-term simulator testing.10

Improved Strength4,5

There are many tests to define a material’s strength. Zimmer Biomet has realized an improvement in tensile strength with Vivacit-E HXPE. Vivacit-E HXPE has antioxidant protection that eliminates the need to re-melt the polyethylene, leading to an improvement in strength. The vitamin E in Vivacit-E HXPE prevents oxidation, resulting in mechanical strength that is retained after accelerated aging for more than 16 times the 2-week industry standard test according to ASTM F2003.2,4,11

Vivacit-E Vitamin E Highly Crosslinked Polyethylene Liners were cleared with the following performance claims:

FDA Traditional 510(k) K120370

Vivacit-E Performance Claims


  1. Bragdon, C. et al. Clinical Multicenter Studies of the Wear Performance of Highly Crosslinked Remelted Polyethylene in THA. Clin Orthop Relat Res (2013) 471:393-402.
  2. Pletcher, D. et al. Vitamin E Grafted HXPE Shows Superior Mechanical Property Retention Compared to Conventional UHMWPE and Sequentially Annealed HXP.  Poster No. 1868, ORS 2014 Meeting.
  3. Zimmer ZRR _WA_2512_12
  4. Zimmer ZRR _WA_2401_11, Rev. 1
  5. Peiserich, M. et al. Retention of Mechanical Properties in a Blended Vitamin E Polyethylene After Extreme Oxidative Challenge. ORS 2013. Poster 1060.
  6. Oral, E. et, al. Crosslinked Vitamin E Blended UHMWPE with Improved Grafting and Wear Resistance. Poster No. 1181. ORS 2011 Meeting.
  7. Oral, E. et, al. Trace amounts of grafted vitamin E protect UHMWPE against squalene-initiated oxidation. Poster No. 1295. ORS 2011 Meeting
  8. Rowell, S. et, al. Detection of Vitamin E in Irradiated UHMWPE by UV-Visible Spectroscopy. Poster No. 1186. ORS 2011 Meeting.
  9. Wolf, C. et, al. Radiation Grafting of Vitamin E to Ultra High Molecular Weight Polyethylene. Poster No. 1178. ORS 2011 Meeting.
  10. Zimmer ZRR_WA_3036_15
  11. Zimmer TM1140.98


Note: Bench testing is not necessarily indicative of clinical performance.


Legal Manufacturer:

Zimmer, Inc.
1800 West Center Street
Warsaw, Indiana 46580 USA

All content herein is protected by copyright, trademarks and other intellectual property rights, as applicable, owned by or licensed to Zimmer Biomet or its affiliates unless otherwise indicated, and must not be redistributed, duplicated or disclosed, in whole or in part, without the express written consent of Zimmer Biomet.  
This material is intended for health care professionals. Distribution to any other recipient is prohibited.
For product information, including indications, contraindications, warnings, precautions, potential adverse effects and patient counseling information, see the package insert and information on this website. To obtain a copy of the current Instructions for Use (IFU) for full prescribing and risk information, please call 1-800-348-2759, press 4 for 411 Technical Support.