Cementless Vanguard® Complete Knee System

The Vanguard® Complete Knee System’s PPS® femur, Regenerex® Primary Tibial Tray and Regenerex® Series-A Patella, provides increased options for cementless arthroplasty and personalized patient care.

PPS® Femur

The Vanguard® Complete Knee System offers ten femoral sizes specifically designed for optimal bone coverage of all patient populations. PPS® coating has been proven to:

  • Maintain the implant’s inherent fatigue strength1-2
  • Provide for early stage bone fixation, helping to prevent micromotion3
  • Provide for late stage bone fixation, helping to offload stresses between implant and bone3

Regenerex® Primary Tibial Tray

The Regenerex® Primary Tibial Tray combines advanced Regenerex® technology with a clinically proven design4 to allow for biologic fixation into the Regenerex® construct to provide for rigid fixation.

  • Four square, non-porous peripheral pegs designed to engage firm cancellous bone for initial biologic fixation 
  • Absence of fixation screws eliminates osteolysis pathways5
  • Compatible with the four primary articulations within the Vanguard® Complete Knee System 
  • Tibial locking mechanism proven to reduce micromotion and backside wear6-7
  • Provides for intraoperative stem selection to match specific patient needs
    • Splined, tapered stem (40 and 80 mm lengths)
    • Cruciate fin (40 and 80 mm lengths)
    • I-beam stem (40 mm length)
    • Taper cap (20 mm length)

Regenerex® Series-A Patella

Regenerex® Patella incorporates Biomet's Regenerex® technology with the Series-A true dome shape, providing surgeons that utilize other Biomet cementless products a complete cementless knee replacement.

  • Three-peg design
  • Increased inner polyethylene thickness while maintaining overall true dome patella geometry
  • Maintains polyethylene thickness throughout range of sizes
  • Maintains consistency of peg location throughout range of sizes


  1. Hahn, H. and Palich, W. Preliminary Evaluation of Porous Metal Surfaced Titanium for Orthopedic Implants. Journal of Biomedical Materials Research. 4(4):571–77, 1970.
  2. Yue, S., et al. The Fatigue Strength of Porous-coated Ti-6% Al-4% V Implant Alloy. Journal of Biomedical Materials Research. 18:1043–58, 1984.
  3. Ritter, M. Twenty-year Survivorship of Cementless Anatomic Graduated Component Total Knee Arthroplasty. The Journal of Arthroplasty. 25(4):507–13, 2010.
  4. Incavo, S., et al. Tibial Plateau Coverage in Total Knee Arthroplasty. Clinical Orthopaedics and Related Research. 299:81–85, 1994.
  5. Peters, P., et al. Osteolysis After Total Knee Arthroplasty Without Cement. The Journal of Bone and Joint Surgery. 74(6):864–76, 1992.
  6. Parks, N., et al. “Modular Tibial Insert Micromotion, A Concern with Contemporary Knee Implants”, Clinical Orthopaedics and Related Research, No. 356, 1998.
  7. Bartel, D., et al. “The Effect of Conformity, Thickness, and Material on Stresses in Ultra-High Molecular Weight Components for Total joint Replacement,” JBJS, Vol. 68-A, No. 7, 1986.

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Talk to your surgeon about whether joint replacement or another treatment is right for you and the risks of the procedure, including the risk of implant wear, loosening or failure, and pain, swelling and infection. Zimmer Biomet does not practice medicine; only a surgeon can answer your questions regarding your individual symptoms, diagnosis and treatment.