Equivabone® Bone Graft Substitute

Composition comparable to human bone

Equivabone® Bone Graft Substitute

EquivaBone Bone Graft Substitute combines the osteoinductivity of demineralized bone matrix (DBM) with the osteoconductivity, moldability, migration resistance, and hard setting characteristics of proprietary nanocrystalline* calcium phosphate technology.1,2 The formulation allows the material to set hard, maintain its shape, and remain in place during bone growth and remodeling.3 Indicated for bone voids or defects that are not intrinsic to the stability of the bony structure.

  • Mineral composition of nanocrystalline* calcium phosphate is comparable to that of human bone
  • Provides a scaffold for new bone growth while undergoing cell mediated remodeling as the bone heals1
  • Continuous osteoconductive scaffold keeps growth factors2 at implant site and is clinically proven, with an average compressive strength of 1-2MPa
  • Can be mixed in a bowl or syringe with blood or saline
  • Provides 15 minutes of working time to allow for intraoperative flexibility
  • Isothermically4,5 sets hard in 10 minutes at 37°C6,7
  • Available in single-patient, single-use kits in volumes of 2.5cc, 5cc and 10cc

Additional Information

*The grain size of the hydroxyapatite (HA) crystals that form as part of the amorphous and crystalline mixture of calcium phosphate sets are on the nanometer scale. The size of the crystalline structures were measured by x-ray diffraction to be less than 100 nanometers.

  1. DHF 080506
  2. Tofighi A, Rosenberg A, Sutaria M, Balata S, Chang J. New generation of synthetic, bioresorbable and injectable calcium phosphate bone substitute materials: Alpha-bsm®, Beta-bsm™ and Gamma-bsm™. J Biomimetics, Biomaterials, and Tissue Engineering. 2009.
  3. Rosenberg AD, Kuhn LT, Gilles de Pelichy L, Jolette J. Osteoinductive composites of calcium phosphate cement and demineralized bone matrix. 2007.
  4. Etex TRE #21022
  5. Etex TRE #030731
  6. Etex TRE#081025
  7. Etex TRE#081011

 

Legal Manufacturer:

ETEX
675 Massachusetts Avenue, 12th Floor
Cambridge, Massachusetts 02139 USA


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